ANXIETY AND DEPRESSION: THINGS TO KNOW. ~Manas Tewari In this era it is quite common that you may roll over the term "depression". Majority of people interpret this term in a different way. However it's absolutely necessary to understand this subject deeply and also understand what happens to our brain when we are in a state of anxiety. What is Depression? Depression is categorized is a MOOD DISORDER. The primary reason for Depression is the excessive secretion of a specific hormone called CORTISOL from the HIPPOCAMPUS region of the brain. Hippocampus is that region of the brain that stores and stimulates memories. Cortisol is released during mental stress and tension. The excessive secretion of cortisol is considered to be the primary cause of MAJOR DEPRESSIVE ORDER. However, there is still a long way of research in the sector of mental health. SYMPTOMS OF DEPRESSION Thoughts off self guilt and self harm arising in the brain Change in sleep patterns either excess or lac